United Nations appeals judges have upheld the convictions of former Bosnian Serb leader Radovan Karadzic for genocide, war crimes and crimes against humanity and increased his sentence from 40 years to life imprisonment.

Karadzic showed almost no reaction as presiding judge Vagn Joensen of Denmark read out a damning judgment that means the 73-year-old former Bosnian strongman is likely to spend the rest of his life behind bars.

In increasing the sentence, Judge Joensen said Karadzic’s original 40-year sentence “underestimates the extraordinary gravity of Karadzic’s responsibility and his integral participation in the most egregious of crimes”.

Former Bosnian Serb leader Radovan Karadzic, second left, rear, rises as judges enter the courtroom of the International Residual Mechanism for Criminal Tribunals in The Hague
Judges enter the courtroom of the International Residual Mechanism for Criminal Tribunals in The Hague (Peter Dejong, Pool/AP)

Defence lawyer Peter Robinson said Karadzic vowed to fight on to clear his name.

“He says that politics triumphed over justice today,” Mr Robinson said.

“The appeals chamber whitewashed an unjust trial and an unfair verdict.”

Mr Robinson said Karadzic felt “moral responsibility” for crimes in Bosnia, but did not believe he was criminally responsible.

He had appealed against his 2016 convictions for genocide, crimes against humanity and war crimes, as well as his sentence for masterminding atrocities in his country’s devastating 1992-95 war – Europe’s bloodiest conflict since the Second World War.

Radovan Karadzic at the International Residual Mechanism for Criminal Tribunals in The Hague
Radovan Karadzic at the International Residual Mechanism for Criminal Tribunals in The Hague (Peter Dejong, Pool/AP)

The former leader is one of the most senior figures tried by The Hague war crimes court.

His case is considered as key in delivering justice for the victims of the conflict, which left more than 100,000 people dead and millions homeless.

Judge Joensen said the trial chamber was wrong to impose just a 40-year sentence, given what he called the “sheer scale and systematic cruelty” of Karadzic’s crimes.

Applause broke out in the public gallery as Judge Joensen passed the new sentence.

Families of victims who travelled to The Hague welcomed the verdict.

The UN court’s conviction and sentencing of ex-Bosnian Serb leader Radovan Karadzic is broadcast in the city hall in Sarajevo
The hearing is broadcast in the city hall in Sarajevo (Darko Bandic/AP)

Mothers of victims, some elderly, wept with apparent relief after watching the ruling read on a screen in Srebrenica.

Bosnian Serb wartime military commander Ratko Mladic was also awaiting an appeal judgment of his genocide and war crimes conviction, which earned him a life sentence.

Both men were convicted of genocide for their roles in the slaughter by Serb forces of 8,000 Muslim men and boys in Bosnia’s eastern Srebrenica region in July 1995.

Prosecutors had appealed against Karadzic’s acquittal on a second count of genocide, which saw Serb forces drive out Muslims and Croats from Serb-controlled villages in a 1992 campaign.

Judges rejected that appeal.

Munira Subasic, of the Mothers of Srebrenica, demonstrates outside the building which houses the International Residual Mechanism for Criminal Tribunals in The Hague, Netherlands
Munira Subasic, of the Mothers of Srebrenica, outside the building which houses the International Residual Mechanism for Criminal Tribunals (Peter Dejong/AP)

At an appeals hearing last year, prosecution lawyer Katrina Gustafson told a five-judge panel that Karadzic “abused his immense power to spill the blood of countless victims. Justice requires that he receive the highest possible sentence – a life sentence”.

Karadzic has always argued that the Bosnian Serb campaigns during the war, which included the bloody siege of the capital Sarajevo, were aimed at defending Serbs.

After his indictment by the tribunal in The Hague, Karadzic remained at large for years before he was arrested in Serbia in 2008 disguised as a new-age therapist.